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Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines

✍ Scribed by Ana Conejo-García; M. Eugenia García-Rubiño; Juan A. Marchal; M. Carmen Núñez; Alberto Ramírez; Sandro Cimino; M. Ángel García; Antonia Aránega; Miguel A. Gallo; Joaquín M. Campos


Book ID
113582983
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
397 KB
Volume
46
Category
Article
ISSN
0223-5234

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Synthesis and Anticancer Activity of (R,
✍ Mónica Díaz-Gavilán; Ana Conejo-García; Olga Cruz-López; María C. Núñez; Duane C 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB 👁 1 views

## Abstract A series of eleven 2‐ and 6‐substituted (__R,S__)‐9‐(2,3‐dihydro‐1,4‐benzoxathiin‐3‐ylmethyl)‐9__H__‐purine derivatives was obtained by applying a standard Mitsunobu protocol that led to a six‐membered ring contraction from (__R,S__)‐3,4‐dihydro‐2__H__‐1,5‐benzoxathiepin‐3‐ol via an epi