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ChemInform Abstract: Synthesis and Anticancer Activity of (RS)-9-(2,3-Dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

✍ Scribed by Ana Conejo-Garcia; M. Eugenia Garcia-Rubino; Juan A. Marchal; M. Carmen Nunez; Alberto Ramirez; Sandro Cimino; M. Angel Garcia; Antonia Aranega; Miguel A. Gallo; Joaquin M. Campos

Publisher
John Wiley and Sons
Year
2011
Weight
31 KB
Volume
43
Category
Article
ISSN
0931-7597

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Synthesis and Anticancer Activity of (R,
Synthesis and Anticancer Activity of (R,S)-9-(2,3-Dihydro-1,4-Benzoxathiin-3-ylmethyl)-9H-Purines
✍ Mónica Díaz-Gavilán; Ana Conejo-García; Olga Cruz-López; María C. Núñez; Duane C 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB 👁 1 views

## Abstract A series of eleven 2‐ and 6‐substituted (__R,S__)‐9‐(2,3‐dihydro‐1,4‐benzoxathiin‐3‐ylmethyl)‐9__H__‐purine derivatives was obtained by applying a standard Mitsunobu protocol that led to a six‐membered ring contraction from (__R,S__)‐3,4‐dihydro‐2__H__‐1,5‐benzoxathiepin‐3‐ol via an epi