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ChemInform Abstract: Synthesis and Biological Activity of 9-(2,6-Difluorobenzyl)-9H-purines Bearing Chlorine.

✍ Scribed by Shigetada Kozai; Tokumi Maruyama

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199942164

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## Abstract A series of eleven 2‐ and 6‐substituted (__R,S__)‐9‐(2,3‐dihydro‐1,4‐benzoxathiin‐3‐ylmethyl)‐9__H__‐purine derivatives was obtained by applying a standard Mitsunobu protocol that led to a six‐membered ring contraction from (__R,S__)‐3,4‐dihydro‐2__H__‐1,5‐benzoxathiepin‐3‐ol via an epi