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Synthesis and Anticancer Activity of 2-Substituted 2,3-Dihydro-1,3,2-benzoxazaphosphorin-4-one and its 2-Oxide Derivatives

โœ Scribed by Krzysztof Kostka; Marek Porada; Julita Graczyk


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
269 KB
Volume
327
Category
Article
ISSN
0365-6233

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3, were synthesized by cyclization of 4-propylthio-1,2-phenylenediamine ( 3) with the corresponding dichlorophosphoryl carbamates/thiocarbamates (2a-J) that were obtained by the addition of alcohols/thiols to isocyanatophosphoryl dichloride (1). The structures of the title compounds were confirme