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Synthesis and antibacterial activity of novel bifunctional macrolides

โœ Scribed by Irini Akritopoulou-Zanze; Kathleen M Phelan; Thomas G Marron; Hong Yong; Zhenkun Ma; Greg G Stone; Melissa M Daly; Dena M Hensey; Angela M Nilius; Stevan W Djuric

Book ID
108073339
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
283 KB
Volume
14
Category
Article
ISSN
0960-894X

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Synthesis and antibacterial activity of
Synthesis and antibacterial activity of novel 4-aryl-[1,2,3]-triazole containing macrolides
โœ David Pereira; Prabhavathi Fernandes ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 874 KB

Two series of novel triazole containing 14-member macrolides having either a cladinose or a 3-pyridyl acetate group at the 3-position of the macrolide ring were synthesized. The in vitro antibacterial activities against S. aureus, S. pneumoniae, S. pyogenes and E. faecalis were determined. Macrolide