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Synthesis and Anti-Tubulin Activity of a 3‘-(4-Azidophenyl)-3‘-dephenylpaclitaxel Photoaffinity Probe

✍ Scribed by Spletstoser, Jared T.; Flaherty, Patrick T.; Himes, Richard H.; Georg, Gunda I.

Book ID
125899738
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
121 KB
Volume
47
Category
Article
ISSN
0022-2623

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✍ A. Thurkauf; B. de Costa; P. Berger; S. Paul; K. C. Rice 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 201 KB

A tritiated photoaffinity ligand for the dopamine reuptake transporter protein, 1-[2-(diphenylmethoxy) ethyl] -4-[ 3-(3 -azidophenyl)-2,3-ditritiopropyl]piperazine, of specific activity 41.8 Cilmmol, was prepared in six steps starting from 1-[2-(diphenylmethoxy)ethyl] piperazine.