Synthesis, stereochemistry and anti-tetr
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G. Evan Boswell; David L. Musso; Ann O. Davis; James L. Kelley; Francis E. Sorok
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Article
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1997
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Journal of Heterocyclic Chemistry
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English
โ 669 KB
A series of bicyclo analogues of several 2-phenylmorpholines were synthesized and tested for anti-tetrabenazine activity in mice. Most of the target compounds were prepared by reaction of 2-bromopropiophenone (22) with the appropriate amino alcohol to form 2-phenylmorpholinols. Reduction of the 2-ph