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Synthesis and anti-microbial activity of new (1-alkyl-1H-1,2,3-triazol-4-yl)methyl-2H-chromene-3-carboxylates: A click chemistry approach

✍ Scribed by Koteswara Reddy, M.; Jayaprakash Rao, Y.; David Krupadanam, G.L.


Book ID
121731977
Publisher
Elsevier
Year
2015
Tongue
English
Weight
495 KB
Volume
19
Category
Article
ISSN
1319-6103

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A series of alkyl 1-heteroaryl-1H-1,2,3-triazole-4-carboxylates 6a-u were synthesised in four steps from methyl (Z)-2-benzyloxycarbonylamino-3-(dimethylamino)prop-2-enoate (1) and heterocyclic amines 2a-s. Triazoles 6a-o were tested against antimycobacterial activity. For the most active compound, n