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Synthesis and Anti-inflammatory Properties of 1α,25-Dihydroxy-16-ene-20-cyclopropyl-24- oxo -vitamin D 3 , a Hypocalcemic, Stable Metabolite of 1α,25-Dihydroxy-16-ene-20-cyclopropyl-vitamin D 3

✍ Scribed by Laverny, Gilles; Penna, Giuseppe; Uskokovic, Milan; Marczak, Stanislaw; Maehr, Hubert; Jankowski, Pawel; Ceailles, Caroline; Vouros, Paul; Smith, Brenden; Robinson, Matthew; Reddy, G. Satyanarayana; Adorini, Luciano


Book ID
118189149
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
294 KB
Volume
52
Category
Article
ISSN
0022-2623

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✍ Rachamallu Aparna; Jagu Subhashini; Karnati R. Roy; G. Satyanarayana Reddy; Matt 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 317 KB

## Abstract Inducible cyclooxygenase‐2 (COX‐2) has been implicated to play a role in inflammation and carcinogenesis and selective COX‐2 inhibitors have been considered as anti‐inflammatory and cancer chemopreventive agents. 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~), the active hormonal form o