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Synthesis and affinity studies of himbacine derived muscarinic receptor antagonists

✍ Scribed by Ling-Jie Gao; Magali Waelbroeck; Sven Hofman; Dirk Van Haver; Marco Milanesio; Davide Viterbo; Pierre J De Clercq

Book ID
108477238
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
117 KB
Volume
12
Category
Article
ISSN
0960-894X

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πŸ“œ SIMILAR VOLUMES

Molecular connectivity study of muscarin
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A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence

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