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Synthesis and activity of partial retro-inverso modified atrial natriuretic factor analogs

✍ Scribed by BERMAN, JUDD M. ;PELTON, JOHN T. ;HASSMAN, C. FRED ;BUCK, STEPHEN H. ;SHEA, PHILLIP J. ;ERTL, PHILLIP ;HEMINGER, EILEEN F. ;BROERSMA, ROBERT J.

Book ID
115098803
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
596 KB
Volume
32
Category
Article
ISSN
0367-8377

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πŸ“œ SIMILAR VOLUMES

Solid-phase synthesis of partially-modif
Solid-phase synthesis of partially-modified retro and retro-inverso ψ[NHCH(CF3)]-peptides
✍ Alessandro Volonterio; Pierfrancesco Bravo; Nathalie Moussier; Matteo Zanda * πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 193 KB

The solid-phase synthesis of a novel class of retro and retro-inverso peptides featuring a 2[NHCH(CF 3 )] surrogate of the classical (NHΓ€CO) retro-peptide bond has been accomplished. Wang resin bound a-amino esters 2 were engaged in Michael-type N-additions with 3-(E-enoyl)-1,3-oxazolidin-2one 3, wh

Synthesis, Structure and Conformation of
Synthesis, Structure and Conformation of Partially-Modified Retro- and Retro-Inverso ψ[NHCH(CF3)]Gly Peptides
✍ Alessandro Volonterio; Stefano Bellosta; Fabio Bravin; Maria Cristina Bellucci; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 401 KB

## Abstract Partially modified retro‐ (PMR) and retro‐inverso (PMRI) ψ[NHCH(CF~3~)]Gly peptides, a conceptually new class of peptidomimetics, have been synthesized in wide structural diversity and variable length by aza‐Michael reaction of enantiomerically pure α‐amino esters and peptides with enan