Synthesis and accumulation of polyamines in rat liver regenerating after treatment with carbon tetrachloride
✍ Scribed by E. Hölttä; Riitta Sinervirta; J. Jänne
- Book ID
- 118854129
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- English
- Weight
- 488 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0006-291X
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We analyzed expression of multidrug resistance (mdr) genes in rat liver during regeneration after partial hepatectomy or carbon tetrachloride-induced necrosis. In situ hybridization revealed that in the normal liver the cellular distribution of mdr transcripts and protein is restricted to hepatocyte
## Abstract The activities of L‐ornithine decarboxylase (EC 4.1.1.17) and S‐adenosyl‐L‐methionine decarboxylase (EC 4.1.1.50) exhibited marked fluctuations in the livers of rats fed 4‐dimethylaminoazobenzene. After 1 month of dye feeding the activity of ornithine decarboxylase rose to a level about