Synthesis, analgesic, anti-inflammatory and ulcerogenic index activities of novel 2-methylthio-3-substituted-5,6-dimethyl thieno [2,3-d] pyrimidin-4(3H)-ones
β Scribed by V. Alagarsamy; D. Shankar; S. Meena; K. Thirumurugan; T. Durai Ananda Kumar
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 151 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0272-4391
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## Abstract magnified image The thienopyridine derivative **2**, obtained from reaction of acetoacetic ester with **1** in the presence of tin tetrachloride, was treated with triphenylphosphine in hexachloroethane and Et~3~N to give iminophosphorane **3**. Iminophosphorane **3** reacted with pheny
## Abstract A series of new 2βsubstituted 3β(4βchlorophenyl)β5,8,9βtrimethylthieno[3β²,2β²:β5,6]pyrido[4,3β__d__]pyrimidinβ4(3__H__)βones **8** were synthesized __via__ an azaβ__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4βchlorophenyl isocyanate to give carbo