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Synthesis, analgesic, anti-inflammatory and ulcerogenic index activities of novel 2-methylthio-3-substituted-5,6-dimethyl thieno [2,3-d] pyrimidin-4(3H)-ones

✍ Scribed by V. Alagarsamy; D. Shankar; S. Meena; K. Thirumurugan; T. Durai Ananda Kumar


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
151 KB
Volume
68
Category
Article
ISSN
0272-4391

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## Abstract A series of new 2‐substituted 3‐(4‐chlorophenyl)‐5,8,9‐trimethylthieno[3β€²,2β€²: 5,6]pyrido[4,3‐__d__]pyrimidin‐4(3__H__)‐ones **8** were synthesized __via__ an aza‐__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4‐chlorophenyl isocyanate to give carbo