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Synthesis, Activity, and Molecular Modeling of New 2,4-Dioxo-5-(naphthylmethylene)-3-thiazolidineacetic Acids and 2-Thioxo Analogues as Potent Aldose Reductase Inhibitors

✍ Scribed by Fresneau, Patrick; Cussac, Max; Morand, Jean-Marc; Szymonski, Barbara; Tranqui, Duc; Leclerc, Gérard


Book ID
111913596
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
158 KB
Volume
41
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Synthesis and Biolo
✍ Simona Rapposelli; Frederico Da Settimo; Maria Digiacomo; Concettina La Motta; A 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 62 KB 👁 1 views

## Abstract A series of the title spirocyclic benzopyran derivatives (XI) (12 examples) is synthesized, which all prove to be selective inhibitors of aldose reductase (ARL2).