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Syntheses of β-Amino Acids and Their N-Alkyl Derivatives

✍ Scribed by ZILKHA, ALBERT; RACHMAN, E. S.; RIVLIN, JOSEPH


Book ID
121256170
Publisher
American Chemical Society
Year
1961
Tongue
English
Weight
631 KB
Volume
26
Category
Article
ISSN
0022-3263

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Asymmetric Syntheses of Derivatives of β-and γ-Aryl and α-Alkyl Amino Acids Using n-BuLi/(-)-Sparteine. -Alkylation of N-Boc and N-arylmethyl or N-cinnamyl p-anisidines with BuLi/(-)-sparteine allows the efficient synthesis of highly enantioenriched derivatives which can be transformed into a varie