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Syntheses of two isotopically labeled CB1 receptor antagonists

✍ Scribed by Boris A. Czeskis


Book ID
112132916
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
890 KB
Volume
55
Category
Article
ISSN
0022-2135

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## Abstract Syntheses of labelled versions of 5‐HT~3~ receptor antagonists, Alosetron and Lurosetron, are described. [^14^C]Alosetron was prepared by routes utilizing either Fischer indolisation of an amidohydrazine or palladium‐mediated cyclisation of an aryl enaminone as key steps. ^2^H and ^13^C