## Abstract Syntheses of labelled versions of 5βHT~3~ receptor antagonists, Alosetron and Lurosetron, are described. [^14^C]Alosetron was prepared by routes utilizing either Fischer indolisation of an amidohydrazine or palladiumβmediated cyclisation of an aryl enaminone as key steps. ^2^H and ^13^C
β¦ LIBER β¦
Synthesis of two isotopically labeled 5-HT1B antagonists
β Scribed by Charles S. Elmore; James E. Hall; Xiaomei Ye; J. Richard Heys
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- French
- Weight
- 79 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2135
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