Syntheses of novel nucleoside dimer analogues containing an acyclic nucleoside and a carbamate linkage
β Scribed by Satoshi Obika; Yoshihiro Takashima; Yasuhide Matsumoto; Kiyonori Kuromaru; Takeshi Imanishi
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 226 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Acyclic nucleoside diphosphonate derivatives of purines and pyrimidines were prepared by Mitsunobu reaction of suitably protected heterocyclic bases with alcohols containing the (phosphonomethyl)phosphanyl moiety. Furthermore, nonhydrolyzable acyclic analogues of dUDP were prepared as p