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Properties of novel oligonucleotide analogues containing an acyclic nucleoside and a carbamate linkage

✍ Scribed by Satoshi Obika; Yoshihiro Takashima; Yasuhide Matsumoto; Atsuko Shimoyama; Yasuo Koishihara; Yoshiyuki Ohsugi; Takefumi Doi; Takeshi Imanishi

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
214 KB
Volume
6
Category
Article
ISSN
0960-894X

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Synthesis and evaluation of oligodeoxynu
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✍ Poul Nielsen; Lars H DreiΓΈe; Jesper Wengel πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 927 KB

Novel flexible oligodeoxynucleotides containing (S)-1-(2,3-dihydroxypropyl)thymine or 2',3'-seco-thymidine nucleoside analogues were synthesized on an automated DNA-synthesizer. Oligodeoxynucleotides with one, two or three acyclic nucleosides incorporated in the middle or in the ends of 17-mers have