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Syntheses of Leukotriene Analogs

✍ Scribed by Bernd Spur; Heiner Jendralla; Attilio Crea; Wilfried Peters; Wolfgang König

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 205 KB
Volume: 319
Category: Article
ISSN: 0365-6233
DOI: 10.1002/ardp.19863190209

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The synthesis of the highly chemotactic leukotriene B3 (la) and of its 6-trans isomer l b by Witrig reaction of the chiral phosphonium salt 3 with the aldehyde 4 is described. A new synthetic route to 4 starting from D-arabinose is reported. ## Synthese voo Leukohien B, Die Synthese des stark che