Syntheses of carboncarbon linked carboranylated porphyrins for boron neutron capture therapy of cancer

✍ Scribed by M.Graça H Vicente; Shankar J Shetty; Anura Wickramasinghe; Kevin M Smith

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 110 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01346-0

✦ Synopsis

Total syntheses of six carboranyl-containing porphyrins bearing 33-44% boron by weight for potential application in boron neutron capture therapy of tumors, are described; these novel compounds feature carbon carbon linkages between the carboranyl groups and the meso-phenyl substituents.