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Carboranyl Bisglycosides for the Treatment of Cancer by Boron Neutron Capture Therapy

โœ Scribed by Lutz F. Tietze; Ulrich Bothe; Ulrich Griesbach; Munekazu Nakaichi; Toshinari Hasegawa; Hiroyuki Nakamura; Yoshinori Yamamoto


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
159 KB
Volume
2
Category
Article
ISSN
1439-4227

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๐Ÿ“œ SIMILAR VOLUMES


Ortho-Carboranyl Glycosides of Glucose,
โœ Lutz F. Tietze; Ulrich Bothe ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 118 KB

Glycosidation of alkynols using the trichloroacetimidate method led to the alkynyl glycosides 2 a,b, 6, 10 and 14 in 53 ยฑ 68 % yield, which by reaction with decaborane( ) afforded the protected peracetylated o-carboranyl glycosides 3 a,b, 7, 11 and 15 in 43 ยฑ 61 % yield. Base-catalyzed solvolysis ga

Studies on the structure of the complex
โœ Brian K. Shull; David E. Spielvogel; Gerald Head; Ramesh Gopalaswamy; Sabapathy ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 214 KB ๐Ÿ‘ 2 views

The complex of L-p-boronophenylalanine (L-p-BPA) with fructose has been used for the past 5 years in clinical trials of boron neutron capture therapy to treat both melanoma and glioblastoma multiforme. However, the structure of this complex in water buffered at physiologic pH has not been establishe