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Syntheses of .alpha.-chloroketones by reaction of silyl enol ethers with copper(II) chloride and iron(III) chloride

โœ Scribed by Ito, Yoshihiko; Nakatsuka, Masashi; Saegusa, Takeo


Book ID
118159374
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
413 KB
Volume
45
Category
Article
ISSN
0022-3263

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Contrary to previous reports, it was found that hydrolysis of silyl enol ethers is superior to the desired condensation in lnCl3-catalyzed aldol reactions of silyl enol ethers with aldehydes in water. The reactions were found to proceed in certain amounts in the presence of a catalytic amount of a L