Syntheses of 6-fluoro-7-piperazin-1-yl-9-cyclopropyl-2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione and 6-fluoro-7-piperazin-1-yl-9-p-fluorophenyl-2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione
✍ Scribed by Daniel T. W. Chu
- Book ID
- 112129611
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1990
- Tongue
- English
- Weight
- 394 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
In the title compound, C 26 H 27 NO 4 , the central ring of the xanthene moiety is planar and the two outer rings are in halfboat conformations. The molecular packing in the crystal structure is stabilized by N-HÁ Á ÁO and C-HÁ Á ÁO hydrogen bonds in addition to van der Waals forces.
In the title compound, C 19 H 15 FI 2 N 2 O 4 , the cyclohexene and morpholinone rings adopt half-chair conformations. The dihedral angle between the benzene and pyrrole rings is 69.0 (2) . The crystal packing is stabilized by C-HÁ Á ÁO and C-HÁ Á ÁF hydrogen bonds. ## Related literature For gene