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Syntheses of 1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine (DPPC) and analogs with 13C- and 2H-labeled choline head groups

✍ Scribed by Sonyuan Lin; Richard I Duclos Jr.; Alexandros Makriyannis

Book ID: 108313382
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 420 KB
Volume: 86
Category: Article
ISSN: 0009-3084
DOI: 10.1016/s0009-3084(97)02672-8

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## Abstract A mixed‐acid monounsaturated lecithin, 1‐palmitoyl‐2‐oleyl‐__sn__‐glycero‐3‐phosphorylcholine (POL), has been synthesized by phospholipase A~2~ digestion of 1,2 dipalmitoyl‐__sn__‐glycero‐3‐phosphorylcholine followed by reacylation of the lysolecithin with oleic anhydride. ^1^H (90 MHz