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Syntheses of 1-(3-oxoalkyl)indole-2-3-diones

✍ Scribed by M. A. Rekhter; F. Z. Makaev; F. V. Babilev; G. N. Grushetskaya; S. V. Rudakov


Publisher
Springer US
Year
1996
Tongue
English
Weight
543 KB
Volume
32
Category
Article
ISSN
0009-3122

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In the title compound, C 14 H 10 N 4 O 2 , the pyridine ring and the isatin unit (indoline-2,3-dione) are nearly coplanar, the dihedral angle being 3.79 (11) . Inter-and intramolecular N-HÁ Á ÁO hydrogen bonding and weak intermolecular C-HÁ Á ÁO hydrogen bonding occur in the crystal structure.

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## Abstract An auto oxidation‐rearrangement product 4 was isolated from a high dilution reaction of ninhydrin with 3,4,5‐trimethoxyaniline in water. A general synthesis of this compound and its derivatives 4–6 was devised by oxidation of tetrahydroindeno[1,2‐__b__]indol‐10‐ones 1–3 with sodium peri