Syntheses d'α,β-fluoroamines et d'α-fluorocetones par action de l'acide fluorhydrique sur des aziridines et des azirines
✍ Scribed by G. Alvernhe; E. Koslowska-Gramsz; S. Lacombe-Bar; A. Laurent
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 263 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Suna~vy : Addition 06 hydrrogen @Qwtid~~o pheny.! azihicbm gives a,B-6.euohoanrin~.Reg~oiobeeectiv.ity and ~&~~eochemib~y 06 the maction am ticubud.
Phenyl azihines add hyd.togen @Lohi&to give, a,@% hy&o&A, a-@uodzeton~.
I -Addition de HF sur des aziridines En 1966, MEYER et all. (1) ont montre que le cycle aziridine des mytomicines pouvait 6tre trans.
📜 SIMILAR VOLUMES
L'aoide :olyphosphorique (APP) est bien oonnu comne un rdactif de choix pour de ncmbreuees rhctions : cyclisations, d&hydratations, 6~ ents par ion carbonizxe, etc . . . (pour quelques revues, voir (1 -3)).
We describe an efficient synthesis of methyl 6-halogeno-6-deoxyglycosides which was performed using Ph$-X2 in DMF solution. Carbohydrate halides could thus be isolated in high yields without preliminary protection of the secondary hydroxyl groups, and were used as intermediates for the E&d