Synthesen mit Mannich-Basen des Indols
✍ Scribed by Thesing, Jan ;Klüssendorf, Siegfried ;Ballach, Peter ;Mayer, Hans
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1955
- Tongue
- English
- Weight
- 817 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0009-2940
No coin nor oath required. For personal study only.
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Stereocontrolled Syntheses of Mannich Bases and γ‐Amino Alcohols The reaction of enantiomerically pure SMP enamines 2 with iminium tetrachloroaluminates 3 yields optically active Mannich bases 4. Diastereoselective reduction of 4 gives γ‐amino alcohols 5 with the desired configuration.