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Synthese von [1]Benzothieno[2,3—d]isoxazol-Derivaten

✍ Scribed by F. Sauter; G. Büyük


Publisher
Springer Vienna
Year
1974
Tongue
English
Weight
279 KB
Volume
105
Category
Article
ISSN
0026-9247

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The reaction of the transient furoisoxazole 4 with dimethyl acetylenedicarboxylate results in the formation of oxepine $&. The boat-shaped structure of s has been confirmed by X-ray crystallography. The experimental findings are in accord with quantum chemical calculations (AMl, PM3).

Synthese von 2,4-Diamino-thieno[2,3-d]py
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Synthesis of 2,4‐Diamino‐thieno[2,3‐__d__]pyrimidines Condensation of 2‐aminothiophene‐3‐carbonitrile (4) with guanidine or sequential addition of CS~2~ and NH~3~ to 4 provides 2,4‐diaminothieno[2,3‐__d__]pyrimidine (7). This compound yields, after sequential addition of __sec__‐BuLi and either [3‐