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Synthese einiger 8-substituierter 2-Methyl-1,2,3,4-tetrahydroisochinoline

✍ Scribed by Max Rey; Tiziana Vergnani; André S. Dreiding

Publisher
John Wiley and Sons
Year
1985
Tongue
German
Weight
484 KB
Volume
68
Category
Article
ISSN
0018-019X

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Eine neue Synthese von 8-Hydroxy-2-methyl-1,2,3,4-tetrahydroisochinolin
✍ Robert W. Gray; Andréa S. Dreiding 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 German ⚖ 312 KB 👁 1 views

**A new Synthesis of 8‐Hydroxy‐2‐methyl‐1,2,3,4‐tetrahydroisoquinoline** __Vilsmeier__ formylation of __N__‐[2‐(3,5‐dimethoxyphenyl)ethyl]‐trifluoroacetamide (**5**) yielded the aldehyde **6**, which under mild basic conditions was hydrolyzed to **7** and cyclized to 6,8‐dimethoxy‐3,4‐dihydroisoqui