Nous avons mis au point la synth&se d'a amino-acides par une nouvelle kthode utilisant l'addition d'organosktallique RMgX sur les imines glyoxyliques I:
Synthese asymetrique d'acides amines α-disubstitues
✍ Scribed by J.A. Bajgrowicz; B. Cossec; Ch. Pigiere; R. Jacquier; Ph. Viallefont
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 179 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Disubstituted amino acids are prepared with good optical yields by enantioselective substitution using Schiff bases between o<-monosubstituted amino acids and (S,S,S) or (R,R,R)-2-hydroxypinan-3-one as chiral reagent. The configuration
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