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Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis

✍ Scribed by Gary S. Firestein; David L. Boyle; Carolyn Yu; Mary M. Paine; Teri D. Whisenand; Nathan J. Zvaifler; William P. Arend

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
941 KB
Volume
37
Category
Article
ISSN
0004-3591

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## Objective: To test if interleukin-1beta (il-1beta), il-1 receptor antagonist (il-1ra), il-4, or il-10 gene polymorphisms could be used as markers of susceptibility or severity in rheumatoid arthritis (ra). ## Methods: The study included 108 patients with early ra followed up for 2 years and 12