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Synovial fibroblasts are novel target cells for the melanocortin peptide α-melanocyte-stimulating hormone

✍ Scribed by Böhm, Markus; Erpenbeck-Leuer, Anne; Kaps, Julia; Apel, Mara; Capellino, Silvia; Grässel, Susanne


Book ID
122686762
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
128 KB
Volume
29
Category
Article
ISSN
0889-1591

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## Abstract ## Objective Recently, we found that human dermal fibroblasts (HDFs) express melanocortin 1 receptors (MC‐1R) that bind α‐melanocyte–stimulating hormone (α‐MSH). In search of novel therapies for scleroderma (systemic sclerosis [SSc]), we used the bleomycin (BLM) model to investigate th