## Abstract ## Objective To investigate a potential interaction between neutrophils and T cells in rheumatoid arthritis (RA), by defining the optimal conditions for induction of class II major histocompatibility complex (MHC) expression on peripheral blood neutrophils in vitro and investigating th
Synovial Class II Antigen Expression and Immune Complex Formation in Rheumatoid Arthritis
β Scribed by KLARESKOG, LARS ;HOLMDAHL, RIKARD ;NORDLING, CECILIA ;TARKOWSKI, ANDREJ ;RUBIN, KRISTOFER
- Book ID
- 114694532
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 506 KB
- Volume
- 221
- Category
- Article
- ISSN
- 0001-6101
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## Abstract Sera and synovial fluids from 88 patients with rheumatoid arthritis were examined for circulating immune complexes by three assays: monoclonal rheumatoid factor radioimmunoassay, Clq binding assay, and Raji cell radioassay. Paired samples were available for 82 patients. Immune complexes
## Abstract Fiftyβsix sera and 33 synovial fluids from rheumatoid arthritis patients were studied to evaluate their capacity to solubilize immune complexes. A decreased function was found in 65% of rheumatoid synovial fluids when compared with 13 osteoarthritis synovial fluids. The decrease of immu