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Synonymous nucleotide substitutions in the neonatal Fc receptor

โœ Scribed by Carolyn A. Gunraj; Bernard J. Fernandes; Gregory A. Denomme

Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
19 KB
Volume
54
Category
Article
ISSN
0093-7711

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In addition to its proposed function in regulating serum IgG levels, the MHC class I-related neonatal Fc receptor (FcRn) is known to play a role in IgG transfer across rodent yolk sac and neonatal intestine. In contrast to humans, for which transplacental transfer of IgG appears to be the only mecha