Synergy of simultaneous administration of ofloxacin and granulocyte colony-stimulating factor in killing ofEscherichia coliby human neutrophils
β Scribed by Andrea Kropec; S. W. Lemmen; H. J. Grundmann; I. Engels; F. D. Daschner
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 433 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0300-8126
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## Abstract ## BACKGROUND. Ewing sarcoma (ES) is a highly vascular malignancy. It has been demonstrated that both angiogenesis and vasculogenesis contribute to the growth of ES tumors. Granulocyteβcolonyβstimulating factor (GβCSF), a cytokine known to stimulate bone marrow (BM) stem cell productio
Granulocyte-macrophage colony-stimulating factor (GM-CSF) (250 microg/m2) was administered subcutaneously to 7 normal volunteers for up to 14 days to study its effects on neutrophil kinetics and function. With treatment, blood neutrophil counts rose gradually to peak at 3 1/2 times baseline by day 1