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Synergy between tetrandrine and FK 506 in prevention of diabetes in BB rats

โœ Scribed by Irving Lieberman; Brian V. Heil; W.Kim Seow; Y.H. Thong

Book ID
118345826
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
359 KB
Volume
53
Category
Article
ISSN
0024-3205

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Preventive effect of a new immunosuppres
Preventive effect of a new immunosuppressant FK-506 on insulitis and diabetes in non-obese diabetic mice
โœ J. Miyagawa; K. Yamamoto; T. Hanafusa; N. Itoh; C. Nakagawa; A. Otsuka; H. Katsu ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 296 KB

We investigated the effect of an immunosuppressant FK-506 on histological change of islets, the onset of diabetes, and the change of spleen cell subsets in female non-obese diabetic mice. Mice administered intraperitoneally with FK-506 from 5 to 20weeks of age showed marked suppression of mononuclea