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Synergistic killing of human leukemia cells by antioxidants and trichostatin A

✍ Scribed by Jiuhong Kang; Jie Chen; Dawei Zhang; Wanming Da; Yingxian Ou

Book ID
105992000
Publisher
Springer
Year
2004
Tongue
English
Weight
454 KB
Volume
54
Category
Article
ISSN
0344-5704

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Synchronous populations of HeLa S3 cells suffer synergistic killing during S phase in the presence of 0.5-5 mM hydroxyurea together with 5-10 mM caffeine. Both the rate and the extent of killing are greater than expected for independent action of the two drugs. Only simultaneous treatment is effecti