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Synergistic effect of PEG-400 and cyclodextrin to enhance solubility of progesterone

✍ Scribed by Indranil Nandi; Michelle Bateson; Mohammad Bari; Hemant N. Joshi

Book ID
111767056
Publisher
Springer US
Year
2003
Tongue
English
Weight
234 KB
Volume
4
Category
Article
ISSN
1530-9932

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The enhancing effects of cyclodextrins (CyDs) on the solubility, the dissolution rate, and the bioavailability of tacrolimus after oral administration to rats were examined and compared with those after administration of a PROGRAF 1 capsule containing the solid dispersion formulation of tacrolimus.