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Synergistic effect of palmitoylcarnitine and the ionophore A23187 on isolated rat mast cells

✍ Scribed by N. Grosman


Publisher
SP Birkhäuser Verlag Basel
Year
1988
Tongue
English
Weight
472 KB
Volume
25
Category
Article
ISSN
1420-908X

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Direct mitogenic effect of ionophore A23
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The Ca2+ ionophore A23187 induces only a weak mitogenic response in cultures of unfractionated mononuclear leukocytes from human blood. When a comitogen, 12-O-tetradecanoyl-phorbol-13-acetate, which by itself is nonmitogenic, is added, a greatly increased cell proliferation is obtained. Highly purif