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Synergistic antinociceptive interaction between aspirin and tramadol, the atypical opioid analgesic, in the rat

✍ Scribed by L. A. Salazar; R. Ventura Martínez; F. J. López-Muñoz


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
607 KB
Volume
36
Category
Article
ISSN
0272-4391

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✦ Synopsis


In order to assess a possible synergistic antinociceptive interactions, the analgesic effects of aspirin per US (acetyl salicylic acid or "ASA"), a nonsteroidal anti-inflammatory drug (NSAID), and tramadol S.C. (TRA), an atypical opioid analgesic, administered either separately or in combination were determined in a model of pain-induced functional impairment in the rat, groups of six rats received either vehicle,


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