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Synergism of Leu–Lys rich antimicrobial peptides and chloramphenicol against bacterial cells

✍ Scribed by Yoonkyung Park; Soon Nang Park; Seong-Cheol Park; Sun Oh Shin; Jin-Young Kim; Sung-Jin Kang; Mi-Hyun Kim; Chan-Young Jeong; Kyung-Soo Hahm


Book ID
103823361
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
427 KB
Volume
1764
Category
Article
ISSN
1570-9639

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Candidacidal mechanism of a Leu/Lys-rich
✍ Peng Wang; Yong Hai Nan; Song Yub Shin 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 854 KB

## Abstract We investigated the mechanism of candidacidal action of a Lys/Leu‐rich α‐helical model antimicrobial peptide (K~9~L~8~W) and its diastereomeric peptide (D~9~‐K~9~L~8~W) composed of D,L‐amino acids. K~9~L~8~W killed completely __Candida albicans__ within 30 min, but D~9~‐K~9~L~8~W killed