Expression of oncogenic K-ras and loss o
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Shujie Zhao; Yubao Wang; Lin Cao; Michel M. Ouellette; James W. Freeman
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Article
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2010
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John Wiley and Sons
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French
⚖ 863 KB
## Abstract Activating mutation of __K‐ras__ and inactivation of __DPC4__ are two common genetic alterations that occur in the development and progression of pancreatic ductal adenocarcinomas (PDAC). A separate common event in PDAC progression is increased expression of phosphotyrosine kinase recep