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Symmetrically-substituted decalin-based scaffolds

✍ Scribed by Zoi F Plyta; Eberhard Heller; Françoise Dumas; Christine Miet; Jacqueline Mahuteau; Jean d'Angelo *; Juan Caturla; Marie-Elise Tran Huu Dau

Book ID
104210155
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
148 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

The synthesis of a chiral scaffold was achieved by coupling a decalintriol platform with a NH-Boc protected α-ethylenic γ-amino acid. The two side chains of this molecule strongly self-associate through intramolecular hydrogen bonding involving the NH-Boc residues.

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