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Symmetric bis-benzimidazoles: new sequence-selective DNA-binding molecules

โœ Scribed by Neidle, Stephen; Rayner, Emma L.; Simpson, Ian J.; Smith, Nicola J.; Mann, John; Baron, Anne; Opoku-Boahen, Yaw; Fox, Keith R.; Hartley, John A.; Kelland, Lloyd R.


Book ID
118276133
Publisher
Royal Society of Chemistry
Year
1999
Tongue
English
Weight
168 KB
Volume
10
Category
Article
ISSN
1359-7345

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Synthesis of a novel dimeric bis-benzimi
โœ Xiao-Wen Sun; Stephen Neidle; John Mann ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 66 KB

We describe the synthesis of bis(3-{4-[2%-(4-methoxyphenyl)-3H,3%H-[5,5%]bibenzimidazolyl-2-yl]phenoxy}propyl)methylamine 8, which has high affinity for the oligonucleotide sequence [A.T] 4 -[G.C]-[A.T] 4 .