Switching to adefovir monotherapy after emergence of lamivudine-resistant mutations in patients with liver cirrhosis
β Scribed by Y.-F. Liaw; C.-M. Lee; R.-N. Chien; C.-T. Yeh
- Book ID
- 108885846
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 412 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1352-0504
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## Abstract No study has reported on the comparative effect of adefovir (ADV) addβon lamivudine (LAM) versus switching to entecavir (ETV) in LAMβresistant patients with chronic hepatitis B. From October 2007 to September 2008, 92 consecutive LAMβresistant patients were enrolled (47 LAMβ+βADV and 45
Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance in treatment-naΓ―ve chronic hepatitis B patients, the association of ADV resistance with previous lamivudine (LAM) resistance is not well understood. We compared the emergence of the ADV-resistant mutations rt
## Abstract Factors influencing the therapeutic efficacy of adefovir dipivoxil added to continuing lamivudine have not been elucidated in lamivudineβresistant patients with type B chronic hepatitis. The viral mutations influencing the efficacy of treatment with adefovir dipivoxil were investigated