Loss of lamivudine resistance mutations after patients switched to adefovir dipivoxil therapy
β Scribed by Christopher Westland; Craig Gibbs; Michael Miller; Mark Sullivan; John Fry; Carol Brosgart; Michael Wulfsohn; Shelly Xiong
- Book ID
- 118564931
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 162 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0168-8278
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π SIMILAR VOLUMES
Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance in treatment-naΓ―ve chronic hepatitis B patients, the association of ADV resistance with previous lamivudine (LAM) resistance is not well understood. We compared the emergence of the ADV-resistant mutations rt
## Abstract Factors influencing the therapeutic efficacy of adefovir dipivoxil added to continuing lamivudine have not been elucidated in lamivudineβresistant patients with type B chronic hepatitis. The viral mutations influencing the efficacy of treatment with adefovir dipivoxil were investigated