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SWAP-70 regulates mast cell FcϵRI-mediated signaling and anaphylaxis

✍ Scribed by Raja R. Sivalenka; Manoj Sinha; Rolf Jessberger


Book ID
102168415
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
474 KB
Volume
38
Category
Article
ISSN
0014-2980

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Comparison of FcϵRI- and FcγRI-mediated
✍ Yoshimichi Okayama; Christine Tkaczyk; Dean D. Metcalfe; Alasdair M. Gilfillan 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB

## Abstract We have demonstrated that CD34^+^ IFN‐γ‐treated human mast cells (HuMC) express functional FcγRI and that aggregation of these receptors leads to mediator release. As the signaling pathways linking FcγRI aggregation to mediator release are unknown, we examined FcγRI‐dependent activation