𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines

✍ Scribed by Jun Hamaguchi; Hiroaki Nakagawa; Masato Takahashi; Takeaki Kudo; Naoya Kamiyama; Bailong Sun; Takahiro Oshima; Yuji Sato; Kisaburo Deguchi; Satoru Todo; Shin-Ichiro Nishimura

Book ID
119901969
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
765 KB
Volume
6
Category
Article
ISSN
1476-4598

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Role of hMLH1 promoter hypermethylation
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines
✍ Christian N. Arnold; Ajay Goel; C. Richard Boland πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 432 KB πŸ‘ 1 views

## Abstract Loss of DNA mismatch repair (MMR) occurs in 10–15% of sporadic colorectal cancer, is usually caused by hMLH1 hypermethylation, and has been shown to confer resistance to various chemotherapeutic reagents, including 5‐fluorouracil (5‐FU). We tested the hypothesis that demethylation of th