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SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells

✍ Scribed by Huilei Xu; Ihor R Lemischka; Avi Ma'ayan


Book ID
115023738
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
627 KB
Volume
4
Category
Article
ISSN
1752-0509

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Cdk1 is required for the self-renewal of
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## Abstract Cyclin‐dependent kinase 1 (Cdk1) is indispensible for the early development of the embryo. However, its role in maintaining the undifferentiated state of the embryonic stem (ES) cells remains unknown. In this study, we dissected the function of Cdk1 in mouse ES cells by RNA‐interference